How a well-adapting immune system remembers

An adaptive agent predicting the future state of an environment must weigh trust in new observations against prior experiences. In this light, we propose a view of the adaptive immune system as a dynamic Bayesian machinery that updates its memory repertoire by balancing evidence from new pathogen en...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 116; číslo 18; s. 8815
Hlavní autori:	Mayer, Andreas, Balasubramanian, Vijay, Walczak, Aleksandra M, Mora, Thierry
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 30.04.2019
Predmet:	Adaptation, Physiological - immunology Adaptive Immunity - physiology Animals Host-Pathogen Interactions Immunologic Memory - physiology Lymphocytes - physiology Models, Biological immune repertoire Bayesian prediction immune memory biophysics stochastic dynamics
ISSN:	1091-6490, 1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
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