Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form

Hendra virus (HeV) is one of the two prototypical members of the Henipavirus genus of paramyxoviruses, which are designated biosafety level 4 (BSL-4) organisms due to the high mortality rate of Nipah virus (NiV) and HeV in humans. Paramyxovirus cell entry is mediated by the fusion protein, F, in res...

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Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 113; číslo 4; s. 1056 - 1061
Hlavní autori:	Wong, Joyce J W, Paterson, Reay G, Lamb, Robert A, Jardetzky, Theodore S
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 26.01.2016
Predmet:	Amino Acid Sequence Crystallography, X-Ray Disulfides - chemistry HEK293 Cells Hendra Virus - chemistry Humans Molecular Sequence Data Protein Conformation Protein Stability Viral Fusion Proteins - chemistry metastable F-protein stabilization F-protein atomic structure Hendra virus membrane fusion paramyxovirus F protein
ISSN:	1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
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