Muscle Injury Induces Postoperative Cognitive Dysfunction

Postoperative cognitive dysfunction (POCD) is a major complication affecting patients of any age undergoing surgery. This syndrome impacts everyday life up to months after hospital discharge, and its pathophysiology still remains unclear. Translational research focusing on POCD is based on a wide va...

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Bibliographic Details
Published in:	Scientific reports Vol. 10; no. 1; p. 2768
Main Authors:	Guéniot, Lorna, Lepere, Victoria, De Medeiros, Gabriela Ferreira, Danckaert, Anne, Flamant, Patricia, Le Dudal, Marine, Langeron, Olivier, Goossens, Pierre L., Chrétien, Fabrice, Jouvion, Grégory
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 17.02.2020 Nature Publishing Group
Subjects:	14/19 631/378/371 64/110 692/617/375 96/63 Aging - pathology Animal cognition Animal models Animals Behavioral plasticity Brain - pathology Brain - surgery Brain research Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Cognitive ability Cognitive science Critical care CX3C Chemokine Receptor 1 - genetics Cytokines - metabolism Disease Models, Animal Experiments Hippocampus - injuries Hippocampus - pathology Hippocampus - surgery Human health and pathology Humanities and Social Sciences Humans Inflammation Life Sciences Locomotion Long term memory Male Memory Mice Microglia Microglia - pathology Morphology multidisciplinary Muscle, Skeletal - injuries Muscle, Skeletal - metabolism Muscle, Skeletal - pathology Muscle, Skeletal - surgery Nerve growth factor Nerve Growth Factor - metabolism Pathophysiology Postoperative Cognitive Complications - etiology Postoperative Cognitive Complications - metabolism Postoperative Cognitive Complications - pathology Postoperative Complications - etiology Postoperative Complications - metabolism Postoperative Complications - pathology Regeneration Science Science (multidisciplinary) Skeletal muscle Surgery Synaptic plasticity Young adults
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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