Factors Associated with Mortality Among Hospitalized Adults with COVID-19 Pneumonia at a Private Tertiary Hospital in Tanzania: A Retrospective Cohort Study

The emergence of the novel coronavirus disease 2019 (COVID-19) has caused millions of deaths worldwide. There has been paucity of data for hospitalized African patients suffering from COVID-19. This study aimed to identify factors associated with in-hospital mortality in patients suffering from COVI...

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Veröffentlicht in:International journal of general medicine Jg. 14; S. 5431 - 5440
Hauptverfasser: Kassam, Nadeem, Aghan, Eric, Aziz, Omar, Mbithe, Hanifa, Hameed, Kamran, Shah, Reena, Surani, Salim, Orwa, James, Somji, Samina
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New Zealand Dove Medical Press Limited 01.01.2021
Taylor & Francis Ltd
Dove
Dove Medical Press
Schlagworte:
Adults
Analysis
Bacterial pneumonia
China
Cohort analysis
Comorbidity
Coronaviruses
COVID-19
Critical care
Diabetes
Emergency medical care
factors
Health aspects
hospital
Hospital patients
Hospitalization
Hospitals
Hypertension
Infectious diseases
Internal medicine
Laboratories
Medical records
Medical research
Medicine
Medicine, Experimental
Mortality
Original Research
Oxygen saturation
Pandemics
Patients
Pneumonia
Population
Public health
Risk factors
Severe acute respiratory syndrome coronavirus 2
Tanzania
Tazobactam
China
Tanzania
Africa
COVID-19
mortality
hospital
Tanzania
factors
ISSN:1178-7074, 1178-7074
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Zusammenfassung:The emergence of the novel coronavirus disease 2019 (COVID-19) has caused millions of deaths worldwide. There has been paucity of data for hospitalized African patients suffering from COVID-19. This study aimed to identify factors associated with in-hospital mortality in patients suffering from COVID-19 in Tanzania. This was a single center, retrospective, observational cohort study in adult patients hospitalized with confirmed COVID-19 infection. Demographics, clinical pattern, laboratory and radiological investigations associated with increased odds of mortality were analyzed. Of the 157 patients, 107 (68.1%) patients survived and 50 (31.8%) died. Mortality was highest in patients suffering with severe (26%) and critical (68%) forms of the disease. The median age of the cohort was 52 years (IQR 42-61), majority of patients were male (86%) and of African origin (46%), who presented with fever (69%), cough (62%) and difficulty in breathing (43%). Factors that were associated with mortality among our cohort were advanced age (OR 1.07, 95% CI 1.03-1.11), being overweight and obese (OR 9.44, 95% CI 2.71-41.0), suffering with severe form of the disease (OR 4.77, 95% CI 1.18-25.0) and being admitted to the HDU and ICU (OR 6.68, 95% CI 2.06-24.6). The overall in-hospital mortality was 31.8%. Older age, obesity, the severe form of the disease and admission to the ICU and HDU were major risk factors associated with in-hospital mortality.
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ISSN:1178-7074
1178-7074
DOI:10.2147/IJGM.S330580