Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

The hippocampus is one of the most affected areas in Alzheimer's disease (AD) . Moreover, this structure hosts one of the most unique phenomena of the adult mammalian brain, namely, the addition of new neurons throughout life . This process, called adult hippocampal neurogenesis (AHN), confers...

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Vydáno v:	Nature medicine Ročník 25; číslo 4; s. 554 - 560
Hlavní autoři:	Moreno-Jiménez, Elena P, Flor-García, Miguel, Terreros-Roncal, Julia, Rábano, Alberto, Cafini, Fabio, Pallas-Bazarra, Noemí, Ávila, Jesús, Llorens-Martín, María
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Nature Publishing Group 01.04.2019
Témata:	Adult Aging Alzheimer Disease - pathology Alzheimer's disease Biomarkers - metabolism Brain Cell Differentiation Controlled conditions Dentate gyrus Dentate Gyrus - pathology Doublecortin Domain Proteins Hippocampal plasticity Hippocampus Hippocampus - pathology Humans Identification methods Maturation Microtubule-Associated Proteins - metabolism Neurogenesis Neurons Neuropeptides - metabolism Physiology
ISSN:	1078-8956, 1546-170X, 1546-170X
On-line přístup:	Získat plný text
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