Explaining the 25-year decline of serum cholesterol by dietary changes and use of lipid-lowering medication in Finland

To assess to what extent the observed dietary changes and increased use of lipid-lowering medication can explain the almost 20 % decline in serum cholesterol (referring to serum total cholesterol) level observed from 1982 to 2007 in Finland. Predicted changes of serum cholesterol were calculated by...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Public health nutrition Ročník 13; číslo 6A; s. 932 - 938
Hlavní autoři: Valsta, Liisa M, Tapanainen, Heli, Sundvall, Jouko, Laatikainen, Tiina, Männistö, Satu, Pietinen, Pirjo, Vartiainen, Erkki
Médium: Journal Article
Jazyk:angličtina
Vydáno: Cambridge, UK Cambridge University Press 01.06.2010
Témata:
administration & dosage
Adult
Age groups
Anticholesteremic Agents
Anticholesteremic Agents - therapeutic use
antilipemic agents
blood
blood lipids
Butter
Cholesterol
Cholesterol - administration & dosage
Cholesterol - blood
Cross-Sectional Studies
Diet
Diet - standards
Diet - trends
Diet Surveys
dietary fat
Dietary Fats
Dietary Fats - administration & dosage
Dietary Fats - standards
Drug Utilization
Drugs
eating habits
Fatty Acids
Fatty Acids - administration & dosage
Female
Finland
Food
Food consumption
food intake
gender differences
human nutrition
Humans
Laboratories
Lipids
Male
Medication
men
Middle Aged
nutrient intake
Nutrition research
nutritional adequacy
Polls & surveys
saturated fatty acids
Sex Factors
Software
Statins
therapeutic use
Trans fats
Trans Fatty Acids
Trans Fatty Acids - administration & dosage
Treatment Outcome
trends
women
Finland
United States > US
Medication
Food consumption
Fatty acids
Cholesterol
Finland
ISSN:1368-9800, 1475-2727, 1475-2727
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:To assess to what extent the observed dietary changes and increased use of lipid-lowering medication can explain the almost 20 % decline in serum cholesterol (referring to serum total cholesterol) level observed from 1982 to 2007 in Finland. Predicted changes of serum cholesterol were calculated by the Keys' equation assuming the effect of trans fatty acids to be similar to SFA and using the dietary intake data of the national dietary surveys between 1982 and 2007. The effect of medication was estimated based on the information on use of lipid-lowering medication among survey participants. The predicted serum cholesterol levels were compared with observed changes in analysed serum cholesterol levels. Four cross-sectional population surveys, in 1982, 1992, 2002 and 2007, in the provinces of North Karelia, Northern Savo and Southwestern Finland. A total of 2325 men and 2638 women aged 26-64 years selected randomly from the national population register for the four surveys. Changes in dietary fat quality and cholesterol intake explain 0.70 mmol/l (65 %) of the decrease in men and 0.65 mmol/l (60 %) of the decrease in women in all subjects. Decline in dietary SFA intake is the main explanatory factor (47 % in men and 41 % in women) for the changes. The impact of lipid-lowering medication on observed cholesterol levels was found to be 16 % among men and 7 % among women. The decrease in serum cholesterol levels in Finland can be explained mainly by dietary changes, especially changes in fat quality. The effect of lipid-lowering medication is less significant.
Bibliografie:http://dx.doi.org/10.1017/S1368980010001126
ark:/67375/6GQ-HGV219GW-L
ArticleID:00112
PII:S1368980010001126
istex:FA105C223A44E9B9F0F979086FE3230DD49B0343
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1368-9800
1475-2727
1475-2727
DOI:10.1017/S1368980010001126