Multiomics Analysis Reveals Significant Disparities in the Oral Microbiota and Metabolites Between Pregnant Women with and without Periodontitis

Our study investigated the disparities and correlations between oral microbiota and metabolites in pregnant patients with and without periodontitis. Subgingival plaque samples from all subjects were collected for shotgun metagenomic sequencing and broad-target metabolomics analysis. Forty pathogens,...

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Vydáno v:	Infection and drug resistance Ročník 17; s. 4665 - 4683
Hlavní autoři:	Zhao, Min, Yang, Changyi, Zhu, Linhong, Guo, Xiaoqian, Ma, Haiyan, Luo, Yuanhao, Wang, Qi, Chen, Juanjuan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New Zealand Dove Medical Press Limited 01.01.2024 Taylor & Francis Ltd Dove Dove Medical Press
Témata:	Alcohol Amino acids Bacteria Bacterial pneumonia biomarkers identification Biosynthesis Carbohydrate metabolism Correlation analysis Dentists Diabetes Folic acid Genetic testing Gum disease Immune response Metabolites Metabolomics Metagenomics microbial metabolites profiling Microbiota Microbiota (Symbiotic organisms) Microorganisms Muscle contraction Oral hygiene oral microbiota composition Original Research Pathogens Periodontitis Phenols Pneumonia predicted functional modules Pregnancy pregnancy-induced periodontitis Pregnant women Premature birth Public-private sector cooperation Pyruvic acid Rankings Signal transduction Smooth muscle Somatotropin Teeth TOR protein Type 2 diabetes Womens health China predicted functional modules biomarkers identification microbial metabolites profiling oral microbiota composition Pregnancy-induced periodontitis
ISSN:	1178-6973, 1178-6973
On-line přístup:	Získat plný text
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