Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials

Materials engineered to elicit targeted cellular responses in regenerative medicine must display bioligands with precise spatial and temporal control. Although materials with temporally regulated presentation of bioadhesive ligands using external triggers, such as light and electric fields, have rec...

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Bibliographic Details
Published in:	Nature materials Vol. 14; no. 3; pp. 352 - 360
Main Authors:	Lee, Ted T., García, José R., Paez, Julieta I., Singh, Ankur, Phelps, Edward A., Weis, Simone, Shafiq, Zahid, Shekaran, Asha, del Campo, Aránzazu, García, Andrés J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.03.2015 Nature Publishing Group
Subjects:	639/301/54 Activation Adhesion Adhesives Animals Biocompatibility Biocompatible Materials - chemistry Biomaterials Biomedical materials Cell adhesion Cell adhesion & migration Cell Adhesion - drug effects Cell Adhesion - immunology Cell Adhesion - radiation effects Cell Adhesion Molecules - adverse effects Cell Adhesion Molecules - radiation effects Cell Line Condensed Matter Physics Drug Eruptions - immunology Fibroblasts - drug effects Fibroblasts - immunology Fibroblasts - pathology Humans Hydrogels In vivo testing In vivo tests Light Male Materials Science Mice Mice, Inbred BALB C Nanotechnology Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - immunology NIH 3T3 Cells Oligopeptides - adverse effects Oligopeptides - radiation effects Optical and Electronic Materials Peptides Studies Surgical implants
ISSN:	1476-1122, 1476-4660, 1476-4660
Online Access:	Get full text
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