Bioimage analysis of Shigella infection reveals targeting of colonic crypts

Few studies within the pathogenic field have used advanced imaging and analytical tools to quantitatively measure pathogenicity in vivo. In this work, we present a novel approach for the investigation of host-pathogen processes based on medium-throughput 3D fluorescence imaging. The guinea pig model...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 112; H. 25; S. E3282
Hauptverfasser:	Arena, Ellen T, Campbell-Valois, Francois-Xavier, Tinevez, Jean-Yves, Nigro, Giulia, Sachse, Martin, Moya-Nilges, Maryse, Nothelfer, Katharina, Marteyn, Benoit, Shorte, Spencer L, Sansonetti, Philippe J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 23.06.2015
Schlagworte:	Animals Colon - microbiology Dysentery, Bacillary - pathology Guinea Pigs Humans Intestinal Mucosa - microbiology Shigella flexneri - pathogenicity Shigella flexneri bioimage analysis host–pathogen interactions intestinal crypts tissue microbiology
ISSN:	1091-6490, 1091-6490
Online-Zugang:	Weitere Angaben
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