Improving reporting of observational studies of interventions: The TARGET guideline

Emulating a target trial when conducting an observational study of interventions can reduce the likelihood of design-related biases. The TARGET guideline aims to improve the reporting transparency of observational studies emulating a target trial and help readers appraise and apply the results.

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Bibliographic Details
Published in:PLoS medicine Vol. 22; no. 10; p. e1004787
Main Authors: Hansford, Harrison J., McAuley, James H., Cashin, Aidan G.
Format: Journal Article
Language:English
Published: United States Public Library of Science 15.10.2025
Public Library of Science (PLoS)
Subjects:
Clinical trials
Guidelines as Topic
Humans
Medical research
Medicine, Experimental
Methods
Observational studies
Observational Studies as Topic - standards
Research Design - standards
Australia
ISSN:1549-1676, 1549-1277, 1549-1676
Online Access:Get full text
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Description
Summary:Emulating a target trial when conducting an observational study of interventions can reduce the likelihood of design-related biases. The TARGET guideline aims to improve the reporting transparency of observational studies emulating a target trial and help readers appraise and apply the results.
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content type line 23
ISSN:1549-1676
1549-1277
1549-1676
DOI:10.1371/journal.pmed.1004787