A dosimetric comparison of helical tomotherapy treatment delivery with real-time adaption and no motion correction

[Display omitted] •Testing a helical tomotherapy system equipped with kV imaging and surface guidance.•A unified testing framework compared real-time adaption versus no motion correction.•Average reduction in 2 %/2 mm γ-fail rate was 17.3 % across 5 lung traces.•Average reduction in 2 %/2 mm γ-fail...

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Bibliographic Details
Published in:Physics and imaging in radiation oncology Vol. 34; p. 100741
Main Authors: Hindmarsh, Jonathan, Crowe, Scott, Johnson, Julia, Sengupta, Chandrima, Walsh, Jemma, Dieterich, Sonja, Booth, Jeremy, Keall, Paul
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01.04.2025
Elsevier
Subjects:
Helical tomotherapy
MLC tracking
Organ motion
Real-time adaptive radiotherapy
Technical Note
Real-time adaptive radiotherapy
Organ motion
Helical tomotherapy
MLC tracking
ISSN:2405-6316, 2405-6316
Online Access:Get full text
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Summary:[Display omitted] •Testing a helical tomotherapy system equipped with kV imaging and surface guidance.•A unified testing framework compared real-time adaption versus no motion correction.•Average reduction in 2 %/2 mm γ-fail rate was 17.3 % across 5 lung traces.•Average reduction in 2 %/2 mm γ-fail rate was 11.8 % across 3 prostate traces.•Helical tomotherapy system performed comparably to other real-time adaptive methods. This study assesses the ability of a helical tomotherapy system equipped with kV imaging and optical surface guidance to adapt to motion traces in real-time. To assess the delivery accuracy with motion, a unified testing framework was used. The average 2 %/2 mm γ-fail rates across all lung traces were 0.1 % for motion adapted and 17.4 % for no motion correction. Average 2 %/2 mm γ-fail rates across all prostate traces were 0.4 % for motion adapted and 12.2 % for no motion correction. Real-time motion adaption was shown to improve the accuracy of dose delivered to a moving phantom compared with no motion adaption. MeSH Keywords: Radiotherapy, image-guided; Radiation therapy, targeted.
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ISSN:2405-6316
2405-6316
DOI:10.1016/j.phro.2025.100741