Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors

The development of new CRISPR-Cas genome editing tools continues to drive major advances in the life sciences. Four classes of CRISPR-Cas-derived genome editing agents-nucleases, base editors, transposases/recombinases and prime editors-are currently available for modifying genomes in experimental s...

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Vydané v:	Nature biotechnology Ročník 38; číslo 7; s. 824 - 844
Hlavní autori:	Anzalone, Andrew V, Koblan, Luke W, Liu, David R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Nature Publishing Group 01.07.2020
Predmet:	CRISPR CRISPR-Cas Systems - genetics DNA Breaks, Double-Stranded Editing Endonucleases - genetics Gene Editing - methods Genome - genetics Genome editing Genomes Humans Nuclease Recombinases - genetics Transposases - genetics
ISSN:	1087-0156, 1546-1696, 1546-1696
On-line prístup:	Získať plný text
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