Distinct Actions of Insulin-Like Growth Factors (IGFs) on Placental Development and Fetal Growth: Lessons from Mice and Guinea Pigs

Placental insufficiency is thought to be a key factor in many cases of intrauterine growth restriction which complicates about 6% of pregnancies in western countries. Understanding the molecular control of placental and fetal growth is essential to identifying diagnostic and therapeutic targets to i...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 29; pp. 42 - 47
Main Authors:	Roberts, C.T., Owens, J.A., Sferruzzi-Perri, A.N.
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Oxford Elsevier Ltd 01.03.2008 Elsevier
Subjects:	Animals Biological and medical sciences Embryology: invertebrates and vertebrates. Teratology Female Fetal Development - physiology Fetal growth Fundamental and applied biological sciences. Psychology Guinea Pigs Humans IGF-I IGF-II IGF2R Insulin-Like Growth Factor I - physiology Insulin-Like Growth Factor II - physiology Internal Medicine Mice Obstetrics and Gynecology Placenta - physiology Placental transport Pregnancy Receptor, IGF Type 1 - physiology Receptor, IGF Type 2 - physiology Trophoblast invasion Fetal growth Placental transport IGF-I Trophoblast invasion IGF2R IGF-II Vertebrata Fetal development Insulin like growth factor Guinea pig Mammalia Placenta Mouse Fetal membrane Growth Animal Rodentia
ISSN:	0143-4004, 1532-3102
Online Access:	Get full text
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