Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Atherosclerotic lesions are known for their cellular heterogeneity, yet the molecular complexity within the cells of human plaques has not been fully assessed. Using single-cell transcriptomics and chromatin accessibility, we gained a better understanding of the pathophysiology underlying human athe...

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Vydané v:	Circulation research Ročník 127; číslo 11; s. 1437
Hlavní autori:	Depuydt, Marie A C, Prange, Koen H M, Slenders, Lotte, Örd, Tiit, Elbersen, Danny, Boltjes, Arjan, de Jager, Saskia C A, Asselbergs, Folkert W, de Borst, Gert J, Aavik, Einari, Lönnberg, Tapio, Lutgens, Esther, Glass, Christopher K, den Ruijter, Hester M, Kaikkonen, Minna U, Bot, Ilze, Slütter, Bram, van der Laan, Sander W, Yla-Herttuala, Seppo, Mokry, Michal, Kuiper, Johan, de Winther, Menno P J, Pasterkamp, Gerard
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 06.11.2020
Predmet:	atherosclerosis cardiovascular disease genome-wide association study single-cell analysis
ISSN:	1524-4571, 1524-4571
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