Catalytic Synthesis of 8‐Membered Ring Compounds via Cobalt(III)‐Carbene Radicals

The metalloradical activation of o‐aryl aldehydes with tosylhydrazide and a cobalt(II) porphyrin catalyst produces cobalt(III)‐carbene radical intermediates, providing a new and powerful strategy for the synthesis of medium‐sized ring structures. Herein we make use of the intrinsic radical‐type reac...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 59; no. 27; pp. 11073 - 11079
Main Authors:	Zhou, Minghui, Lankelma, Marianne, Vlugt, Jarl Ivar, Bruin, Bas
Format:	Journal Article
Language:	English
Published:	WEINHEIM Wiley 26.06.2020 Wiley Subscription Services, Inc John Wiley and Sons Inc
Edition:	International ed. in English
Subjects:	8-membered diene rings Aldehydes Aromatic compounds carbene radicals Catalysts Chemical synthesis Chemistry Chemistry, Multidisciplinary Cobalt Cyclic compounds Density functional theory dibenzocyclooctenes Divergence Enantiomers Hydrogen bonds Intermediates Mathematical analysis metalloradicals Physical Sciences Ring structures Science & Technology CYCLOADDITION carbene radicals 8-membered diene rings CONSTRUCTION dibenzocyclooctenes metalloradicals CYCLOPROPANATION INDOLINES cobalt LIGAND VERSATILE SYNTHONS CYCLIZATION
ISSN:	1433-7851, 1521-3773, 1521-3773
Online Access:	Get full text
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