The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial

The present study aimed to evaluate the clinical and radiographic effects of autologous platelet concentrate (APC) on the healing of intra-bony defects filled with β-tricalcium phosphate (β-TCP) and covered with collagen membranes. This study included 30 defects of 14 systemically healthy subjects....

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Vydané v:	European Oral Research Ročník 53; číslo 1; s. 38 - 43
Hlavní autori:	Kudyar, Nitin, Dani, Nitin, Abullais, Shahab Saquib, AlQahtani, Nabeeh A., Gupta, Aashima, Attar, Nilofar
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Turkey Istanbul University Press 01.01.2019 İstanbul Üniversitesi Yayınları Istanbul University Faculty of Dentistry Istanbul University
Predmet:	Calcium phosphate Clinical trials Collagen Comparative analysis Diş Hekimliği intra-bony defects latelet rich plasma periodontal regeneration periodontitis Tıp Transmission Control Protocol/Internet Protocol (Computer network protocol) β‑tricalcium phosphate India İstanbul Türkiye periodontal regeneration intra-bony defects platelet rich plasma betatricalcium phosphate periodontitis Intra-bony defects β‑tricalcium phosphate
ISSN:	2630-6158, 2149-2352, 2651-2823, 2651-2823, 2149-4592
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Popis
Shrnutí:	The present study aimed to evaluate the clinical and radiographic effects of autologous platelet concentrate (APC) on the healing of intra-bony defects filled with β-tricalcium phosphate (β-TCP) and covered with collagen membranes. This study included 30 defects of 14 systemically healthy subjects. All of them had, at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probing pocket depth (PPD) was 6 mm. Clinical and imaging examination was performed both at baseline and at 3, 6, and 9 months after surgery. Both the test and control group revealed a significant reduction in all variables when compared with the base line. Mean reduction of the PPD in two groups at each follow-up time point showed no significant difference. Means of the clinical attachment gain of the same groups were significantly different (p<0.05). Mean gingival recession at 3 month was not significant. However, the means of gingival recession coverage of two groups were significantly different at 6 and 9 months (p<0.05 for both). Sites treated with APC are more likely to demonstrate more clinical attachment gain and recession coverage at the end of 9 month compared to those without APC.
Bibliografia:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2630-6158 2149-2352 2651-2823 2651-2823 2149-4592
DOI:	10.26650/eor.20192207101715