The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial

The present study aimed to evaluate the clinical and radiographic effects of autologous platelet concentrate (APC) on the healing of intra-bony defects filled with β-tricalcium phosphate (β-TCP) and covered with collagen membranes. This study included 30 defects of 14 systemically healthy subjects....

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Bibliographic Details
Published in:European Oral Research Vol. 53; no. 1; pp. 38 - 43
Main Authors: Kudyar, Nitin, Dani, Nitin, Abullais, Shahab Saquib, AlQahtani, Nabeeh A., Gupta, Aashima, Attar, Nilofar
Format: Journal Article
Language:English
Published: Turkey Istanbul University Press 01.01.2019
İstanbul Üniversitesi Yayınları
Istanbul University Faculty of Dentistry
Istanbul University
Subjects:
Calcium phosphate
Clinical trials
Collagen
Comparative analysis
Diş Hekimliği
intra-bony defects
latelet rich plasma
periodontal regeneration
periodontitis
Tıp
Transmission Control Protocol/Internet Protocol (Computer network protocol)
β‑tricalcium phosphate
India
İstanbul
Türkiye
periodontal regeneration
intra-bony defects
platelet rich plasma
betatricalcium phosphate
periodontitis
Intra-bony defects
β‑tricalcium phosphate
ISSN:2630-6158, 2149-2352, 2651-2823, 2651-2823, 2149-4592
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Summary:The present study aimed to evaluate the clinical and radiographic effects of autologous platelet concentrate (APC) on the healing of intra-bony defects filled with β-tricalcium phosphate (β-TCP) and covered with collagen membranes. This study included 30 defects of 14 systemically healthy subjects. All of them had, at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probing pocket depth (PPD) was 6 mm. Clinical and imaging examination was performed both at baseline and at 3, 6, and 9 months after surgery. Both the test and control group revealed a significant reduction in all variables when compared with the base line. Mean reduction of the PPD in two groups at each follow-up time point showed no significant difference. Means of the clinical attachment gain of the same groups were significantly different (p<0.05). Mean gingival recession at 3 month was not significant. However, the means of gingival recession coverage of two groups were significantly different at 6 and 9 months (p<0.05 for both). Sites treated with APC are more likely to demonstrate more clinical attachment gain and recession coverage at the end of 9 month compared to those without APC.
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ISSN:2630-6158
2149-2352
2651-2823
2651-2823
2149-4592
DOI:10.26650/eor.20192207101715