Quality control initiative on the evaluation of the dysmegakaryopoiesis in myeloid neoplasms: Difficulties in the assessment of dysplasia

•The presence of micromegakaryocytes correlates strongly with myeloid neoplasia.•Micromegakaryocytes can be identified reliably.•Multinucleated megakaryocytes are not specific for myeloid neoplasia.•Cytoplasmic dysplasia is not useful in recognising MDS.•‘Possibly dysplastic’ cells should be exclude...

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Veröffentlicht in:	Leukemia research Jg. 45; S. 75 - 81
Hauptverfasser:	Goasguen, Jean E., Bennett, John M., Bain, Barbara J., Brunning, Richard D., Vallespí, Maria-Teresa, Tomonaga, Masao, Zini, Gina, Renault, Alain
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.06.2016 Elsevier
Schlagworte:	Cancer Cell Shape Cell Size Dysmegakaryocytopoiesis Dysmegakaryopoiesis Dysmyelopoiesis Dysplastic features Hematologic Neoplasms - pathology Hematology Hematology, Oncology and Palliative Medicine Human health and pathology Humans Life Sciences Megakaryocyte Progenitor Cells Megakaryocytes Megakaryocytes - pathology Myelodysplastic syndrome Myelodysplastic Syndromes - diagnosis Myeloproliferative Disorders - diagnosis Quality Control Tissues and Organs Dysplastic features Megakaryocytes Dysmegakaryopoiesis Dysmegakaryocytopoiesis Myelodysplastic syndrome Dysmyelopoiesis myelodysplastic syndrome
ISSN:	0145-2126, 1873-5835, 1873-5835, 0145-2126
Online-Zugang:	Volltext
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