CD24 is a genetic modifier for risk and progression of prostate cancer

CD24 plays an oncogenic role in the onset and progression of various human cancers, including prostate cancer. In the present study, we identified two linkage disequilibrium blocks with four recombination hotspot motifs in human CD24 locus. To elucidate whether genetic variants of CD24 are associate...

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Veröffentlicht in:	Molecular carcinogenesis Jg. 56; H. 2; S. 641 - 650
Hauptverfasser:	Zhang, Yifan, Li, Bingjin, Zhang, Xingyi, Sonpavde, Guru P., Jiao, Kenneth, Zhang, Andrea, Zhang, Guangxin, Sun, Mei, Chu, Chengjing, Li, Feng, Wang, Lizhong, Cui, Ranji, Liu, Runhua
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.02.2017
Schlagworte:	Aged Aged, 80 and over Alleles Biomarkers Case-Control Studies CD24 CD24 Antigen - analysis CD24 Antigen - genetics Disease Progression Gene Expression Regulation, Neoplastic Genetic diversity Genetic Predisposition to Disease Genetics Genotype Genotype & phenotype Health risks Humans Linkage Disequilibrium Male Middle Aged mRNA Odds Ratio Polymorphism Polymorphism, Genetic Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide Prostate - pathology Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Protein expression Recombination hot spots Ribonucleic acid Risk factors RNA tumor progression Tumors prostate cancer polymorphism tumor progression CD24
ISSN:	0899-1987, 1098-2744
Online-Zugang:	Volltext
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