Macrophages are important mediators of either tumor- or inflammation-induced lymphangiogenesis

The lymphatic system provides important functions for tissue fluid homeostasis and immune response. Lymphangiogenesis, the formation of new lymphatics, comprises a series of complex cellular events in vitro or in vivo, e.g., proliferation, differentiation, and sprouting. Recent evidence has implied...

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Bibliographic Details
Published in:	Cellular and molecular life sciences : CMLS Vol. 69; no. 6; pp. 897 - 914
Main Author:	Ji, Rui-Cheng
Format:	Journal Article
Language:	English
Published:	Basel SP Birkhäuser Verlag Basel 01.03.2012 Springer Nature B.V
Subjects:	Angiogenesis Animals Antigens, CD - physiology Biochemistry Biomedical and Life Sciences Biomedicine Bone marrow CD11b antigen Cell Adhesion Molecules - physiology Cell Adhesion Molecules, Neuronal - physiology Cell Biology Cells Homeostasis Humans Immune response Inflammation Inflammation - physiopathology Lectins, C-Type - physiology Life Sciences Lymphangiogenesis Lymphatic system Lymphocyte receptors Macrophage Activation Macrophage colony-stimulating factor Macrophages Macrophages - physiology Malignancy Mannose Receptor Mannose-Binding Lectins - physiology Neoplasms - physiopathology NF-κB protein Phenotypes Receptors, Cell Surface - physiology Receptors, CXCR4 - physiology Receptors, Lymphocyte Homing - physiology Review SDF-1 protein Signal Transduction Toll-Like Receptor 4 - physiology Tumor Microenvironment Tumor necrosis factor-α Tumors Vascular endothelial growth factor Vascular endothelial growth factor C Vascular Endothelial Growth Factor C - physiology Vascular Endothelial Growth Factor Receptor-3 - physiology Lymphatic endothelial cells VEGFR-2/-3 Tumor Inflammation Macrophages Lymphangiogenesis VEGF-A/-C/-D
ISSN:	1420-682X, 1420-9071, 1420-9071
Online Access:	Get full text
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