The silent threat: asymptomatic parasitemia and malaria transmission

Scale-up of malaria control interventions has resulted in a substantial decline in global malaria morbidity and mortality. Despite this achievement, there is evidence that current interventions alone will not lead to malaria elimination in most malaria-endemic areas and additional strategies need to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Expert review of anti-infective therapy Jg. 11; H. 6; S. 623 - 639
Hauptverfasser: Lindblade, Kim A, Steinhardt, Laura, Samuels, Aaron, Kachur, S Patrick, Slutsker, Laurence
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Taylor & Francis 01.06.2013
Expert Reviews Ltd
Informa Healthcare
Schlagworte:
Adolescent
Adult
Aged
Animals
Anopheles - parasitology
antimalarial
asymptomatic
Asymptomatic Infections
Child
Child, Preschool
Disease transmission
Disease Vectors
Distribution
elimination
Humans
Infant
Infant, Newborn
infection
interventions
Malaria
Malaria, Falciparum - diagnosis
Malaria, Falciparum - immunology
Malaria, Falciparum - parasitology
Malaria, Falciparum - transmission
Medical research
Medicine, Experimental
Middle Aged
parasite
Parasitemia - diagnosis
Parasitemia - immunology
Parasitemia - parasitology
Parasitemia - transmission
Plasmodium falciparum - physiology
ISSN:1478-7210, 1744-8336, 1744-8336
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Scale-up of malaria control interventions has resulted in a substantial decline in global malaria morbidity and mortality. Despite this achievement, there is evidence that current interventions alone will not lead to malaria elimination in most malaria-endemic areas and additional strategies need to be considered. Use of antimalarial drugs to target the reservoir of malaria infection is an option to reduce the transmission of malaria between humans and mosquito vectors. However, a large proportion of human malaria infections are asymptomatic, requiring treatment that is not triggered by care-seeking for clinical illness. This article reviews the evidence that asymptomatic malaria infection plays an important role in malaria transmission and that interventions to target this parasite reservoir may be needed to achieve malaria elimination in both low- and high-transmission areas.
Bibliographie:ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Feature-3
ObjectType-Review-1
ObjectType-Article-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1478-7210
1744-8336
1744-8336
DOI:10.1586/eri.13.45