Acute effects of pharmacological modifications of fatty acid metabolism on human satiety

The role of NEFA in eating behaviour is still poorly known. Our objective was to examine whether etomoxir (ETO), an inhibitor of NEFA oxidation, or ( − )-hydroxycitrate (HCA), an inhibitor of lipogenesis which may indirectly stimulate NEFA oxidation, alters satiety. Post-lunch satiety was measured i...

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Bibliographic Details
Published in:	British journal of nutrition Vol. 101; no. 12; pp. 1867 - 1877
Main Authors:	Gatta, Blandine, Zuberbuehler, Christine, Arnold, Myrtha, Aubert, Roberte, Langhans, Wolfgang, Chapelot, Didier
Format:	Journal Article
Language:	English
Published:	Cambridge, UK Cambridge University Press 28.06.2009
Subjects:	( − )-Hydroxycitrate 3-Hydroxybutyric Acid 3-Hydroxybutyric Acid - blood Adult analysis Analysis of Variance Appetite Area Under Curve Biological and medical sciences Biomarkers Biomarkers - blood Blood Blood Glucose Blood Glucose - analysis blood plasma Citrates Citrates - pharmacology diet dinner drug effects drug evaluation Eating Eating behavior eating habits Energy Intake enzyme inhibitors Epoxy Compounds Epoxy Compounds - pharmacology etomoxir Fatty acid oxidation fatty acids Fatty Acids, Nonesterified Fatty Acids, Nonesterified - metabolism Feeding. Feeding behavior food intake Fundamental and applied biological sciences. Psychology ghrelin Ghrelin - blood glucose Humans Hunger hydroxycitrate Hypoglycemic Agents Hypoglycemic Agents - pharmacology ideal body weight insulin Insulin - blood lactates Lactic Acid Lactic Acid - blood Leptin Leptin - blood Lipid Metabolism Lipid Metabolism - drug effects lipogenesis lipolysis lunch Male men metabolism NEFA non-essential fatty acids Oxidation pharmacology Satiation Satiation - drug effects satiety Single-Blind Method Triglycerides Triglycerides - analysis Vertebrates: anatomy and physiology, studies on body, several organs or systems Young Adult Fatty acid oxidation Eating ( − )-Hydroxycitrate NEFA Leptin Human Modification Acute Lipids Metabolism Fatty acids Vertebrata Mammalia (―)-Hydroxycitrate Satiety Oxidation
ISSN:	0007-1145, 1475-2662, 1475-2662
Online Access:	Get full text
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