Osteoprotegerin Is Associated With Silent Coronary Artery Disease in High-Risk but Asymptomatic Type 2 Diabetic Patients

OBJECTIVE:--Osteoprotegerin (OPG) is an inhibitor of osteoclastogenesis, which has been recently involved in atherosclerosis. The relationship between coronary atherosclerosis and OPG has never been studied in asymptomatic type 2 diabetic patients. RESEARCH DESIGN AND METHODS--This is a nested case-...

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Bibliographic Details
Published in:	Diabetes care Vol. 28; no. 9; pp. 2176 - 2180
Main Authors:	Avignon, Antoine, Sultan, Ariane, Piot, Christophe, Elaerts, Stéphane, Cristol, Jean Paul, Dupuy, Anne Marie
Format:	Journal Article
Language:	English
Published:	Alexandria, VA American Diabetes Association 01.09.2005
Subjects:	adiponectin Adrenergic beta-Agonists Aged analysis Associated diseases and complications Atherosclerosis Biological and medical sciences Biomarkers Biomarkers - blood blood C-reactive protein Cardiology. Vascular system Cardiovascular disease case-control studies Cholesterol Complications and side effects coronary artery disease Coronary Disease Coronary Disease - blood Coronary Disease - diagnosis Coronary Disease - epidemiology Coronary heart disease Diabetes Diabetes Mellitus, Type 2 Diabetes Mellitus, Type 2 - blood Diabetes. Impaired glucose tolerance Diabetic Angiopathies Diabetic Angiopathies - blood Diabetic Angiopathies - diagnosis Diabetic Angiopathies - epidemiology diagnosis diagnostic use Dipyridamole Electrocardiography Endocrine pancreas. Apud cells (diseases) Endocrinopathies epidemiology Exercise Test Female Glycated Hemoglobin Glycated Hemoglobin A - analysis Glycoproteins Glycoproteins - blood Health risk assessment Heart high density lipoprotein cholesterol Humans image analysis kidney diseases Lipids Lipids - blood low density lipoprotein cholesterol Male Medical imaging Medical sciences Middle Aged Multivariate Analysis noninsulin-dependent diabetes mellitus odds ratio Osteoprotegerin patients Physiological aspects Platelet Aggregation Inhibitors Receptors, Cytoplasmic and Nuclear Receptors, Cytoplasmic and Nuclear - blood Receptors, Tumor Necrosis Factor Receptors, Tumor Necrosis Factor - blood regression analysis Risk Factors Type 2 diabetes France Endocrinopathy Vascular disease Type 2 diabetes Human High risk Atherosclerosis Cardiovascular disease Metabolic diseases Complication Asymptomatic Coronary heart disease Osteoprotegerin
ISSN:	0149-5992, 1935-5548
Online Access:	Get full text
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