A genome-wide association study identifies a novel East Asian–specific locus for dementia with Lewy bodies in Japanese subjects

Background Dementia with Lewy bodies (DLB) is the second most common type of degenerative dementia in older patients. As with other multifactorial diseases, the pathogenesis results from interactions of environmental and genetic factors. The genetic basis of DLB is not yet fully understood. Recent g...

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Veröffentlicht in:	Molecular medicine (Cambridge, Mass.) Jg. 31; H. 1; S. 87 - 11
Hauptverfasser:	Mitsumori, Risa, Asanomi, Yuya, Morizono, Takashi, Shigemizu, Daichi, Niida, Shumpei, Ozaki, Kouichi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 06.03.2025 BMC
Schlagworte:	Aged Aged, 80 and over Biomedical and Life Sciences Biomedicine Case-Control Studies Dementia with Lewy bodies East Asian People - genetics Expression quantitative trait locus analysis Female Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Humans Japan Lewy Body Disease - genetics Male Molecular Medicine Polymorphism, Single Nucleotide Trans-Ethnic meta-Analysis Transcriptome-Wide association analysis Japan Transcriptome-Wide association analysis Trans-Ethnic meta-Analysis Expression quantitative trait locus analysis Genome-Wide association study Dementia with Lewy bodies
ISSN:	1528-3658, 1076-1551, 1528-3658
Online-Zugang:	Volltext
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