Genome‐wide pathogenesis interpretation using a heat diffusion‐based systems genetics method and implications for gene function annotation

Background Genetics is best dedicated to interpreting pathogenesis and revealing gene functions. The past decade has witnessed unprecedented progress in genetics, particularly in genome‐wide identification of disorder variants through Genome‐Wide Association Studies (GWAS) and Phenome‐Wide Associati...

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Veröffentlicht in:	Molecular genetics & genomic medicine Jg. 8; H. 10; S. e1456 - n/a
Hauptverfasser:	Quan, Yuan, Zhang, Qing‐Ye, Lv, Bo‐Min, Xu, Rui‐Feng, Zhang, Hong‐Yu
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States John Wiley & Sons, Inc 01.10.2020 John Wiley and Sons Inc Wiley
Schlagworte:	Algorithms Annotations Binding sites Consortia Deoxyribonucleic acid Disease DNA Drug development drug discovery Electronic health records gene function annotation Gene regulation Genes Genetic algorithms Genetic disorders Genetics Genome-wide association studies Genomes Genomics Genotype & phenotype Genotypes Mathematical analysis Medical Subject Headings-MeSH Mutation Networks Original Pathogenesis Phenome‐Wide Association Studies Phenotypes Protein interaction Proteins Research methodology systems genetics Transcription pathogenesis systems genetics drug discovery gene function annotation Phenome-Wide Association Studies Genome-Wide Association Studies
ISSN:	2324-9269, 2324-9269
Online-Zugang:	Volltext
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