Pain-related anxiety, sex, and co-use of alcohol and prescription opioids among adults with chronic low back pain
•Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and opioids.•Future work should continue to investigate sex differences in these associations.•Pain-related anxiety may be a transdiagnostic facto...
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| Vydáno v: | Drug and alcohol dependence Ročník 214; s. 108171 |
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| Hlavní autoři: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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Ireland
Elsevier B.V
01.09.2020
Elsevier Science Ltd |
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| ISSN: | 0376-8716, 1879-0046, 1879-0046 |
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| Abstract | •Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and opioids.•Future work should continue to investigate sex differences in these associations.•Pain-related anxiety may be a transdiagnostic factor underlying alcohol-opioid use.
Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men.
This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors.
Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse.
These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males. |
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| AbstractList | Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men.BACKGROUNDBoth alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men.This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors.METHODSThis study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors.Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse.RESULTSPain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse.These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males.CONCLUSIONSThese findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males. Background: Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men. Methods: This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors. Results: Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse. Conclusions: These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males. Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men. This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, M = 43.95) who completed an online survey assessing health behaviors. Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse. These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males. •Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and opioids.•Future work should continue to investigate sex differences in these associations.•Pain-related anxiety may be a transdiagnostic factor underlying alcohol-opioid use. Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men. This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors. Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse. These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males. |
| ArticleNumber | 108171 |
| Author | Powers, Jessica M. Garey, Lorra Ditre, Joseph W. LaRowe, Lisa R. Zvolensky, Michael J. Rogers, Andrew H. |
| AuthorAffiliation | 1 Department of Psychology, Syracuse University 2 Department of Psychology, University of Houston |
| AuthorAffiliation_xml | – name: 2 Department of Psychology, University of Houston – name: 1 Department of Psychology, Syracuse University |
| Author_xml | – sequence: 1 givenname: Lisa R. orcidid: 0000-0002-1869-0906 surname: LaRowe fullname: LaRowe, Lisa R. organization: Department of Psychology, Syracuse University, United States – sequence: 2 givenname: Jessica M. surname: Powers fullname: Powers, Jessica M. organization: Department of Psychology, Syracuse University, United States – sequence: 3 givenname: Lorra surname: Garey fullname: Garey, Lorra organization: Department of Psychology, University of Houston, United States – sequence: 4 givenname: Andrew H. surname: Rogers fullname: Rogers, Andrew H. organization: Department of Psychology, University of Houston, United States – sequence: 5 givenname: Michael J. surname: Zvolensky fullname: Zvolensky, Michael J. organization: Department of Psychology, University of Houston, United States – sequence: 6 givenname: Joseph W. orcidid: 0000-0003-1137-2849 surname: Ditre fullname: Ditre, Joseph W. email: jwditre@syr.edu organization: Department of Psychology, Syracuse University, United States |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32679522$$D View this record in MEDLINE/PubMed |
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| Keywords | Co-Use Alcohol Pain Chronic pain Opioids |
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| Snippet | •Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and... Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also... Background: Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription... |
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| SubjectTerms | Adult Adults Alcohol Alcohol abuse Alcohol Drinking - epidemiology Alcohol use Alcohols Analgesics, Opioid - therapeutic use Anxiety Anxiety Disorders - drug therapy Back pain Chronic back pain Chronic low back pain Chronic pain Chronic Pain - drug therapy Co-Use Drinking Drinking behavior Ethanol Female Health behavior Humans Low back pain Low Back Pain - chemically induced Low Back Pain - drug therapy Low Back Pain - epidemiology Male Men Middle Aged Narcotics Opioid-Related Disorders - drug therapy Opioid-Related Disorders - epidemiology Opioids Pain Prescription Drug Misuse - statistics & numerical data Prescriptions Prevalence Sex Surveys and Questionnaires Test anxiety |
| Title | Pain-related anxiety, sex, and co-use of alcohol and prescription opioids among adults with chronic low back pain |
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