Pain-related anxiety, sex, and co-use of alcohol and prescription opioids among adults with chronic low back pain

•Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and opioids.•Future work should continue to investigate sex differences in these associations.•Pain-related anxiety may be a transdiagnostic facto...

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Vydané v:Drug and alcohol dependence Ročník 214; s. 108171
Hlavní autori: LaRowe, Lisa R., Powers, Jessica M., Garey, Lorra, Rogers, Andrew H., Zvolensky, Michael J., Ditre, Joseph W.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Ireland Elsevier B.V 01.09.2020
Elsevier Science Ltd
Predmet:
Adult
Adults
Alcohol
Alcohol abuse
Alcohol Drinking - epidemiology
Alcohol use
Alcohols
Analgesics, Opioid - therapeutic use
Anxiety
Anxiety Disorders - drug therapy
Back pain
Chronic back pain
Chronic low back pain
Chronic pain
Chronic Pain - drug therapy
Co-Use
Drinking
Drinking behavior
Ethanol
Female
Health behavior
Humans
Low back pain
Low Back Pain - chemically induced
Low Back Pain - drug therapy
Low Back Pain - epidemiology
Male
Men
Middle Aged
Narcotics
Opioid-Related Disorders - drug therapy
Opioid-Related Disorders - epidemiology
Opioids
Pain
Prescription Drug Misuse - statistics & numerical data
Prescriptions
Prevalence
Sex
Surveys and Questionnaires
Test anxiety
Co-Use
Alcohol
Pain
Chronic pain
Opioids
ISSN:0376-8716, 1879-0046, 1879-0046
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Shrnutí:•Pain-related anxiety was positively associated with alcohol and opioid use/misuse.•Pain-related anxiety was positively associated with co-use of alcohol and opioids.•Future work should continue to investigate sex differences in these associations.•Pain-related anxiety may be a transdiagnostic factor underlying alcohol-opioid use. Both alcohol and prescription opioid use/misuse are highly prevalent among individuals with chronic pain. Co-use of alcohol and prescription opioids is also common, despite contraindications due to increased risk of negative health effects and mortality. There is evidence that pain-related anxiety (i.e., the tendency to respond to pain with anxiety or fear) may be associated with heavier drinking and prescription opioid use/co-use, and that these associations may be especially salient among men. This study is the first examination of pain-related anxiety in relation to hazardous alcohol use, prescription opioid use/misuse, and alcohol-opioid co-use. Participants included 1812 adults with chronic low back pain (69 % female, Mage = 43.95) who completed an online survey assessing health behaviors. Pain-related anxiety was positively associated with indices of alcohol (i.e., alcohol-related consequences) and opioid use (i.e., prescription opioid use/misuse, daily opioid consumption). Of note, sex moderated associations between pain-related anxiety and both alcohol-related consequences and prescription opioid misuse. In addition to being associated with alcohol and prescription opioid use, independently, pain-related anxiety was also associated with greater likelihood of endorsing co-use of alcohol and opioids and engaging in concurrent hazardous drinking and prescription opioid misuse. These findings contribute to a growing literature suggesting that pain-related anxiety is an important transdiagnostic factor in pain and alcohol and prescription opioid use/co-use, perhaps especially among males.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
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LRL, JMP, and JWD performed the data analyses and drafted the manuscript. LG, AHR, and MJZ designed the survey and conducted recruitment. All authors contributed to the manuscript and approved the final version of the manuscript for submission.
Contributors
ISSN:0376-8716
1879-0046
1879-0046
DOI:10.1016/j.drugalcdep.2020.108171