The mouse X chromosome is enriched for sex-biased genes not subject to selection by meiotic sex chromosome inactivation

Sex chromosomes are subject to sex-specific selective evolutionary forces 1 , 2 . One model predicts that genes with sex-biased expression should be enriched on the X chromosome 2 , 3 , 4 , 5 . In agreement with Rice's hypothesis 3 , spermatogonial genes are over-represented on the X chromosome...

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Bibliographic Details
Published in:	Nature genetics Vol. 36; no. 6; pp. 642 - 646
Main Authors:	Khil, Pavel P, Smirnova, Natalya A, Romanienko, Peter J, Camerini-Otero, R Daniel
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.06.2004 Nature Publishing Group
Subjects:	Agriculture Animal Genetics and Genomics Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Chromosomes Classical genetics, quantitative genetics, hybrids Datasets Dosage Compensation, Genetic Endodeoxyribonucleases Esterases - deficiency Esterases - genetics Female Females Fundamental and applied biological sciences. Psychology Gene Expression Gene Function Genetic aspects Genetics of eukaryotes. Biological and molecular evolution Genome Human Genetics Inactivation letter Male Meiosis - genetics Mice Mice, Knockout Models, Genetic Ovaries Physiological aspects Pregnancy Sex chromosomes Spermatogenesis Spermatogenesis - genetics Testes Testis Vertebrata X Chromosome - genetics X chromosomes United States New York United States > US Vertebrata Mammalia Gene Mouse Spermatogenesis Selection Rodentia Sex chromosome Meiosis X-Chromosome Inactivation
ISSN:	1061-4036, 1546-1718
Online Access:	Get full text
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