A recombinant vesicular stomatitis virus replicon vaccine protects chickens from highly pathogenic avian influenza virus (H7N1)

Highly pathogenic avian influenza viruses (HPAIV) of subtypes H5 and H7 cause fatal disease in poultry (fowl plague) but also have zoonotic potential. Currently commercially available vaccines often do not provide sufficient protection and do not allow easy discrimination between vaccinated and infe...

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Bibliographic Details
Published in:	Vaccine Vol. 27; no. 8; pp. 1174 - 1183
Main Authors:	Kalhoro, Nazeer H., Veits, Jutta, Rautenschlein, Silke, Zimmer, Gert
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 18.02.2009 Elsevier Elsevier Limited
Subjects:	Allergy and Immunology Animals Antibodies, Viral - blood Antigens Applied microbiology Avian influenza virus Biological and medical sciences Biosafety Bird migration Cell Line Chick Embryo Chickens Cricetinae Fundamental and applied biological sciences. Psychology Genetic Vectors Immunization Immunization, Secondary Influenza A virus - immunology Influenza A Virus, H5N2 Subtype - immunology Influenza A Virus, H7N7 Subtype - genetics Influenza A Virus, H7N7 Subtype - immunology Influenza in Birds - immunology Influenza in Birds - prevention & control Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Injections, Intramuscular Microbiology Miscellaneous Mortality Mutation Neutralization Tests Poultry RNA replicon Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Marker - administration & dosage Vaccines, Marker - immunology Vesicular stomatitis virus Vesiculovirus - genetics Veterinary medicine Virology Virus Shedding - immunology Viruses Zoonoses Avian influenza virus Vesicular stomatitis virus RNA replicon Farming animal Poultry Recombinant virus Orthomyxoviridae Zoopathogen Vaccine Virus Pathogenicity Mononegavirales Vertebrata Vesiculovirus Influenzavirus A Avian influenzavirus Rhabdoviridae Chicken Aves Veterinary
ISSN:	0264-410X, 1873-2518
Online Access:	Get full text
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