Pattern recognition receptors and the inflammasome in kidney disease

Key Points Toll-like receptors (TLRs), nucleotide-binding oligomerization domain receptors (NLRs) and the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome regulate inflammatory and repair processes in the kidneys TLRs prevent invasion and growth of pathogens in the urinary tract...

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Veröffentlicht in:	Nature reviews. Nephrology Jg. 10; H. 7; S. 398 - 414
Hauptverfasser:	Leemans, Jaklien C., Kors, Lotte, Anders, Hans-Joachim, Florquin, Sandrine
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.07.2014 Nature Publishing Group
Schlagworte:	692/420/254 692/420/256 692/699/1585/1681 692/699/1585/4 Acute Kidney Injury - microbiology Acute Kidney Injury - physiopathology Adaptor Proteins, Signal Transducing - physiology Animals Carrier Proteins - immunology Cell receptors Cytokines Development and progression Genetic aspects Homeostasis Humans Immune response Infections Inflammasomes - immunology Inflammation Kidney - immunology Kidney diseases Kidney Diseases - immunology Kidney Transplantation Kinases Medical research Medicine & Public Health Medicine, Experimental Mice Nephrology NLR Family, Pyrin Domain-Containing 3 Protein Pathogens Pathology Pattern recognition Properties Proteins Receptors, Pattern Recognition - immunology review-article Sepsis - complications Toll-Like Receptors - genetics Toll-Like Receptors - immunology Urinary Tract Infections - immunology Urogenital system
ISSN:	1759-5061, 1759-507X, 1759-507X
Online-Zugang:	Volltext
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