Efficient production of astaxanthin in Yarrowia lipolytica through metabolic and enzyme engineering

Astaxanthin is a natural red carotenoid, commonly used as an additive in the pharmaceutical industry and as a nutritional supplement owing to its notable antioxidant benefits. However, a complex biosynthetic pathway poses a challenge to de novo biosynthesis of astaxanthin. Here, Yarrowia lipolytica...

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Vydané v:	Synthetic and systems biotechnology Ročník 10; číslo 3; s. 737 - 750
Hlavní autori:	Abdullah, Chalak Najat, Liu, Mengsu, Chen, Qihang, Gao, Song, Zhang, Changtai, Liu, Shike, Zhou, Jingwen
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	China Elsevier B.V 01.09.2025 KeAi Publishing Communications Ltd KeAi Publishing KeAi Communications Co., Ltd
Predmet:	Algae Antioxidants Astaxanthin Bacteria Batch culture Biosynthesis Carotene Carotenoids Catalytic activity CRISPR Dietary supplements E coli Enzyme engineering Enzymes Fermentation Genes Genomes Glucose Metabolic engineering Modular enzyme assembly Organelles Original Pharmaceutical industry Plasmids Productivity Subcellular organelles Yarrowia lipolytica Yeast β-Carotene China Shanghai China Modular enzyme assembly Subcellular organelles Enzyme engineering Astaxanthin Yarrowia lipolytica
ISSN:	2405-805X, 2405-805X
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