Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1

Patients with psoriasis have impaired vascular health and increased cardiovascular disease (CVD). Platelets are key players in the pathogenesis of vascular dysfunction in cardiovascular disease and represent therapeutic targets in cardiovascular prevention. The object of this study was to define the...

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Vydané v:	Arteriosclerosis, thrombosis, and vascular biology Ročník 40; číslo 5; s. 1340
Hlavní autori:	Garshick, Michael S, Tawil, Michael, Barrett, Tessa J, Salud-Gnilo, Charissa M, Eppler, Michael, Lee, Angela, Scher, Jose U, Neimann, Andrea L, Jelic, Sanja, Mehta, Nehal N, Fisher, Edward A, Krueger, James G, Berger, Jeffrey S
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.05.2020
Predmet:	Adult Aspirin - administration & dosage Blood Platelets - drug effects Blood Platelets - enzymology Cells, Cultured Cyclooxygenase 1 - blood Cyclooxygenase 1 - genetics Cyclooxygenase Inhibitors - administration & dosage Endothelial Cells - drug effects Endothelial Cells - enzymology Female Humans Male Middle Aged Platelet Activation Platelet Adhesiveness Psoriasis - blood Psoriasis - diagnosis Psoriasis - drug therapy Psoriasis - enzymology Severity of Illness Index Signal Transduction Thromboxane B2 - blood Treatment Outcome endothelium aspirin inflammation psoriasis platelet aggregation
ISSN:	1524-4636, 1524-4636
On-line prístup:	Zistit podrobnosti o prístupe
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