Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1

Patients with psoriasis have impaired vascular health and increased cardiovascular disease (CVD). Platelets are key players in the pathogenesis of vascular dysfunction in cardiovascular disease and represent therapeutic targets in cardiovascular prevention. The object of this study was to define the...

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Bibliographic Details
Published in:	Arteriosclerosis, thrombosis, and vascular biology Vol. 40; no. 5; p. 1340
Main Authors:	Garshick, Michael S, Tawil, Michael, Barrett, Tessa J, Salud-Gnilo, Charissa M, Eppler, Michael, Lee, Angela, Scher, Jose U, Neimann, Andrea L, Jelic, Sanja, Mehta, Nehal N, Fisher, Edward A, Krueger, James G, Berger, Jeffrey S
Format:	Journal Article
Language:	English
Published:	United States 01.05.2020
Subjects:	Adult Aspirin - administration & dosage Blood Platelets - drug effects Blood Platelets - enzymology Cells, Cultured Cyclooxygenase 1 - blood Cyclooxygenase 1 - genetics Cyclooxygenase Inhibitors - administration & dosage Endothelial Cells - drug effects Endothelial Cells - enzymology Female Humans Male Middle Aged Platelet Activation Platelet Adhesiveness Psoriasis - blood Psoriasis - diagnosis Psoriasis - drug therapy Psoriasis - enzymology Severity of Illness Index Signal Transduction Thromboxane B2 - blood Treatment Outcome endothelium aspirin inflammation psoriasis platelet aggregation
ISSN:	1524-4636, 1524-4636
Online Access:	Get more information
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