Ranking non-synonymous single nucleotide polymorphisms based on disease concepts

As the number of non-synonymous single nucleotide polymorphisms (nsSNPs) identified through whole-exome/whole-genome sequencing programs increases, researchers and clinicians are becoming increasingly reliant upon computational prediction algorithms designed to prioritize potential functional varian...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Human genomics Ročník 8; číslo 1; s. 11
Hlavní autori:	Shihab, Hashem A, Gough, Julian, Mort, Matthew, Cooper, David N, Day, Ian NM, Gaunt, Tom R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 30.06.2014 Springer Nature B.V
Predmet:	Algorithms Amino Acid Substitution - genetics Bioinformatics Biomedical and Life Sciences Biomedicine Cancer Computational Biology Human Genetics Humans Internet Markov Chains Metabolic disorders Mutation Mutation - genetics Phenotype Polymorphism, Single Nucleotide - genetics Primary Research Proteins Proteomics Software Studies Training FATHMM PolyPhen SIFT nsSNPs Disease-causing SNV HMMs Bioinformatics Disease-specific
ISSN:	1479-7364, 1473-9542, 1479-7364
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!