The Histone Methyltransferase KMT2B Is Required for RNA Polymerase II Association and Protection from DNA Methylation at the MagohB CpG Island Promoter

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Vydané v:Molecular and Cellular Biology Ročník 33; číslo 7; s. 1383 - 1393
Hlavní autori: Ladopoulos, Vasileios, Hofemeister, Helmut, Hoogenkamp, Maarten, Riggs, Arthur D., Stewart, A. Francis, Bonifer, Constanze
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States American Society for Microbiology 01.04.2013
Taylor & Francis
Predmet:
Animals
Cell Line
chromatin
Chromatin - genetics
Chromatin - metabolism
CpG Islands
DNA Methylation
DNA-directed RNA polymerase
Down-Regulation
embryogenesis
Embryonic Stem Cells - metabolism
Gene Silencing
genes
genomic islands
Histone Methyltransferases
Histone-Lysine N-Methyltransferase - genetics
Histone-Lysine N-Methyltransferase - metabolism
histones
Kinetics
lysine
methyltransferases
Mice
Myeloid-Lymphoid Leukemia Protein - genetics
Myeloid-Lymphoid Leukemia Protein - metabolism
Nuclear Proteins - genetics
Nuclear Proteins - metabolism
Promoter Regions, Genetic
RNA Polymerase II - genetics
RNA Polymerase II - metabolism
transcription (genetics)
ISSN:0270-7306, 1098-5549, 1098-5549
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ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.01721-12