Long-term mechanical durability of dental nanocomposites containing amorphous calcium phosphate nanoparticles

Half of all dental restorations fail within 10 years, with secondary caries and restoration fracture being the main reasons. Calcium phosphate (CaP) composites can release Ca and PO4 ions and remineralize tooth lesions. However, there has been no report on their long‐term mechanical durability. The...

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Vydané v:Journal of biomedical materials research. Part B, Applied biomaterials Ročník 100B; číslo 5; s. 1264 - 1273
Hlavní autori: Moreau, Jennifer L., Weir, Michael D., Giuseppetti, Anthony A., Chow, Laurence C., Antonucci, Joseph M., Xu, Hockin H. K.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2012
Wiley-Blackwell
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ISSN:1552-4973, 1552-4981, 1552-4981
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Shrnutí:Half of all dental restorations fail within 10 years, with secondary caries and restoration fracture being the main reasons. Calcium phosphate (CaP) composites can release Ca and PO4 ions and remineralize tooth lesions. However, there has been no report on their long‐term mechanical durability. The objective of this study was to investigate the wear, thermal‐cycling, and water‐aging of composites containing amorphous calcium phosphate nanoparticles (NACP). NACP of 112‐nm and glass particles were used to fabricate four composites: (1) 0% NACP+75% glass; (2) 10% NACP+65% glass; (3) 15% NACP+60% glass; and (4) 20% NACP+50% glass. Flexural strength and elastic modulus of NACP nanocomposites were not degraded by thermal‐cycling. Wear depth increased with increasing NACP filler level. Wear depths of NACP nanocomposites after 4 × 105 cycles were within the range for commercial controls. Mechanical properties of all the tested materials decreased with water‐aging time. After 2 years, the strengths of NACP nanocomposites were moderately higher than the control composite, and much higher than the resin‐modified glass ionomers. The mechanism of strength loss for resin‐modified glass ionomer was identified as microcracking and air‐bubbles. NACP nanocomposites and control composite were generally free of microcracks and air‐bubbles. In conclusion, combining NACP nanoparticles with reinforcement glass particles resulted in novel nanocomposites with long‐term mechanical properties higher than those of commercial controls, and wear within the range of commercial controls. These strong long‐term properties, plus the Ca‐PO4 ion release and acid‐neutralization capability reported earlier, suggest that the new NACP nanocomposites may be promising for stress‐bearing and caries‐inhibiting restorations. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2012.
Bibliografia:University of Maryland School of Dentistry, ADAF, NIST
ArticleID:JBM32691
ark:/67375/WNG-HXT9DT2L-L
How to cite this article: Moreau JL, Weir MD, Giuseppetti AA, Chow LC, Antonucci JM, Xu Hockin H. K. 2012. Long-term mechanical durability of dental nanocomposites containing amorphous calcium phosphate nanoparticles. J Biomed Mater Res Part B 2012:100B:1264-1273.
istex:3F3A207C9F31EAE456852F1FD3D4464C11150CEB
NIH - No. R01 DE17974; No. DE16416
How to cite this article
Moreau JL, Weir MD, Giuseppetti AA, Chow LC, Antonucci JM, Xu Hockin H. K. 2012. Long‐term mechanical durability of dental nanocomposites containing amorphous calcium phosphate nanoparticles. J Biomed Mater Res Part B 2012:100B:1264–1273.
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ISSN:1552-4973
1552-4981
1552-4981
DOI:10.1002/jbm.b.32691