Thyroid hormones and their placental deiodination in normal and pre-eclamptic pregnancy

Pre-eclampsia is associated with lower serum selenium concentrations and glutathione peroxidase expression/activity; total thyroid hormones are also lower. We hypothesised that the placental selenoprotein deiodinase (D3) will be protected in pre-eclampsia due to the hierarchy of selenoprotein biosyn...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 34; no. 5; pp. 395 - 400
Main Authors:	Kurlak, L.O., Mistry, H.D., Kaptein, E., Visser, T.J., Broughton Pipkin, F.
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 01.05.2013 Elsevier
Subjects:	Adult Biological and medical sciences Deiodinases Embryology: invertebrates and vertebrates. Teratology Female Fetal Blood - chemistry Fundamental and applied biological sciences. Psychology Gene Expression Gestational Age Humans Internal Medicine Iodide Peroxidase - analysis Iodide Peroxidase - genetics Iodide Peroxidase - metabolism Obstetrics and Gynecology Placenta Placenta - enzymology Placenta - metabolism Pre-eclampsia Pre-Eclampsia - blood Pre-Eclampsia - enzymology Pregnancy Pregnancy. Parturition. Lactation RNA, Messenger - analysis Selenium - blood Thyroid hormones Thyroid Hormones - metabolism Thyrotropin - blood Thyroxine - blood Triiodothyronine - blood Vertebrates: reproduction Placenta Pre-eclampsia Thyroid hormones Deiodinases Pregnancy Vertebrata Mammalia Pregnancy disorders Fetal membrane Preeclampsia Thyroid hormone Normal Pregnancy toxemia
ISSN:	0143-4004, 1532-3102, 1532-3102
Online Access:	Get full text
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