Current Approaches to the Treatment of Post-Stroke Aphasia

Aphasia, impairment of language after stroke or other neurological insult, is a common and often devastating condition that affects nearly every social activity and interaction. Behavioral speech and language therapy is the mainstay of treatment, although other interventions have been introduced to...

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Veröffentlicht in:Journal of stroke Jg. 23; H. 2; S. 183 - 201
Hauptverfasser: Fridriksson, Julius, Hillis, Argye Elizabeth
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Korea (South) Korean Stroke Society 01.05.2021
대한뇌졸중학회
Schlagworte:
aphasia
brain
language therapy
Review
speech therapy
stroke
신경과학
Aphasia
Brain
Stroke
Language therapy
Speech therapy
ISSN:2287-6391, 2287-6405
Online-Zugang:Volltext
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Zusammenfassung:Aphasia, impairment of language after stroke or other neurological insult, is a common and often devastating condition that affects nearly every social activity and interaction. Behavioral speech and language therapy is the mainstay of treatment, although other interventions have been introduced to augment the effects of the behavioral therapy. In this narrative review, we discuss advances in aphasia therapy in the last 5 years and focus primarily on properly powered, randomized, controlled trials of both behavioral therapies and interventions to augment therapy for post-stroke aphasia. These trials include evaluation of behavioral therapies and computer-delivered language therapies. We also discuss outcome prediction trials as well as interventional trials that have employed noninvasive brain stimulation, or medications to augment language therapy. Supported by evidence from Phase III trials and large meta-analyses, it is now generally accepted that aphasia therapy can improve language processing for many patients. Not all patients respond similarly to aphasia therapy with the most severe patients being the least likely responders. Nevertheless, it is imperative that all patients, regardless of severity, receive aphasia management focused on direct therapy of language deficits, counseling, or both. Emerging evidence from Phase II trials suggests transcranial brain stimulation is a promising method to boost aphasia therapy outcomes.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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ISSN:2287-6391
2287-6405
DOI:10.5853/jos.2020.05015