Diabetes and altered glucose metabolism with aging

Diabetes and impaired glucose tolerance affect a substantial proportion of older adults. Abnormal glucose metabolism is not a necessary component of aging. Older adults with diabetes and altered glucose status likely represent a subset of the population at high risk for complications and adverse ger...

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Bibliographic Details
Published in:Endocrinology and metabolism clinics of North America Vol. 42; no. 2; p. 333
Main Authors: Kalyani, Rita Rastogi, Egan, Josephine M
Format: Journal Article
Language:English
Published: United States 01.06.2013
Subjects:
Aging
Animals
Diabetes Complications - prevention & control
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - therapy
Glucose Metabolism Disorders - blood
Glucose Metabolism Disorders - epidemiology
Glucose Metabolism Disorders - metabolism
Glucose Metabolism Disorders - therapy
Humans
Insulin - blood
Insulin - metabolism
Insulin Resistance
Insulin Secretion
Insulin-Secreting Cells - metabolism
Precision Medicine
ISSN:1558-4410, 1558-4410
Online Access:Get more information
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Summary:Diabetes and impaired glucose tolerance affect a substantial proportion of older adults. Abnormal glucose metabolism is not a necessary component of aging. Older adults with diabetes and altered glucose status likely represent a subset of the population at high risk for complications and adverse geriatric syndromes. Goals for treatment of diabetes in the elderly include control of hyperglycemia, prevention and treatment of diabetic complications, avoidance of hypoglycemia, and preservation of quality of life. Research exploring associations of dysglycemia and insulin resistance with the development of adverse outcomes in the elderly may ultimately inform use of future glucose-lowering therapies in this population.
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ISSN:1558-4410
1558-4410
DOI:10.1016/j.ecl.2013.02.010