Influence of endometrial nerve fibers and hormones on pain in women with endometriosis

•Women with endometriosis had a higher density of PGP9.5-positive nerve fibers in the endometrium compared to healthy controls.•Higher nerve fiber density was linked to more severe pain (higher VAS score).•No association was found between hormone levels and nerve fiber density, and hormonal treatmen...

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Bibliographic Details
Published in:	European journal of obstetrics & gynecology and reproductive biology Vol. 310; p. 113950
Main Authors:	Sommar, Anton, Bahat, Pinar Yalcin, Özaydin, Ipek Yildiz, Bixo, Marie, Bäckström, Torbjörn, Oral, Engin, Turkmen, Sahruh
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.06.2025
Subjects:	Adult Allopregnanolone Case-Control Studies EHP30 Endometriosis - blood Endometriosis - complications Endometriosis - pathology Endometriosis - physiopathology Endometrium - innervation Endometrium - pathology Estrogen Female Humans Immunohistochemistry Nerve Fibers - pathology Obstetrics and Gynecology Pain Measurement Pelvic Pain - blood Pelvic Pain - etiology Pelvic Pain - pathology PGP9.5 Progesterone Progesterone - blood Symptom severity Immunohistochemistry EHP30 PGP9.5 Estrogen Progesterone Symptom severity Allopregnanolone
ISSN:	0301-2115, 1872-7654, 1872-7654
Online Access:	Get full text
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