Visual Impairment and Blindness Due to Macular Diseases Globally: A Systematic Review and Meta-Analysis

To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy. Meta-analysis. Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting...

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Bibliographic Details
Published in:American journal of ophthalmology Vol. 158; no. 4; pp. 808 - 815
Main Authors: Jonas, Jost B., Bourne, Rupert R.A., White, Richard A., Flaxman, Seth R., Keeffe, Jill, Leasher, Janet, Naidoo, Kovin, Pesudovs, Konrad, Price, Holly, Wong, Tien Y., Resnikoff, Serge, Taylor, Hugh R.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01.10.2014
Elsevier Limited
Subjects:
Age
Blindness
Blindness - epidemiology
Diabetes
Diabetic retinopathy
Disease
Global Health - statistics & numerical data
Humans
Macula Lutea
Macular degeneration
Ophthalmology
Persons with Visual Disabilities - statistics & numerical data
Population
Prevalence
Public health
Retinal Diseases - epidemiology
Studies
Vision, Low - epidemiology
Visual Acuity
Visual impairment
Europe
Sub-Saharan Africa
ISSN:0002-9394, 1879-1891, 1879-1891
Online Access:Get full text
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Summary:To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy. Meta-analysis. Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to macular diseases, with diabetic maculopathy excluded. In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively. In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impaired people, 1 was visually impaired due to macular disease.
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ISSN:0002-9394
1879-1891
1879-1891
DOI:10.1016/j.ajo.2014.06.012