Multi-scale approach for simulating time-delay biochemical reaction systems

This study presents a multi-scale approach for simulating time-delay biochemical reaction systems when there are wide ranges of molecular numbers. The authors construct a new efficient approach based on partitioning into slow and fast subsets in conjunction with predictor–corrector methods. This mul...

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Bibliographic Details
Published in:	IET systems biology Vol. 9; no. 1; pp. 31 - 38
Main Authors:	Niu, Yuanling, Burrage, Kevin, Zhang, Chengjian
Format:	Journal Article
Language:	English
Published:	England The Institution of Engineering and Technology 01.02.2015
Subjects:	Algorithms Biochemistry biological techniques Biology Computational efficiency Computer Simulation Delay delay stochastic simulation algorithm delays Mathematical models method accuracy Models, Biological Models, Chemical modified next reaction method multiscale approach numerical testing Partitioning predictor‐corrector methods Proteins - chemistry Proteins - metabolism Signal Transduction - physiology systems biology time‐delay biochemical reaction systems systems biology numerical testing modified next reaction method time-delay biochemical reaction systems computational efficiency multiscale approach predictor–corrector methods delays biochemistry method accuracy delay stochastic simulation algorithm biological techniques predictor-corrector methods
ISSN:	1751-8849, 1751-8857
Online Access:	Get full text
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