Fates of CD8+ T cells in Tumor Microenvironment

Studies have reported a positive correlation between elevated CD8+ T cells in the tumor microenvironment (TME) and good prognosis in cancer. However, the mechanisms linking T cell tumor-infiltration and tumor rejection are yet to be fully understood. The cells and factors of the TME facilitate tumor...

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Veröffentlicht in:	Computational and structural biotechnology journal Jg. 17; S. 1 - 13
Hauptverfasser:	Maimela, Nomathamsanqa Resegofetse, Liu, Shasha, Zhang, Yi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.01.2019 Research Network of Computational and Structural Biotechnology Elsevier
Schlagworte:	biotechnology CD8+ T cell differentiation CD8+ T cell fates CD8+ T cell trafficking CD8-positive T-lymphocytes cell growth immunosuppression neoplasms prognosis Review T cell exhaustion Tumor microenvironment T cell exhaustion CD8+ T cell differentiation CD8+ T cell fates Tumor microenvironment CD8+ T cell trafficking
ISSN:	2001-0370, 2001-0370
Online-Zugang:	Volltext
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