Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

Mitochondrial ribosomes translate membrane integral core subunits of the oxidative phosphorylation system encoded by mtDNA. These translation products associate with nuclear-encoded, imported proteins to form enzyme complexes that produce ATP. Here, we show that human mitochondrial ribosomes display...

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Veröffentlicht in:	Cell Jg. 167; H. 2; S. 471
Hauptverfasser:	Richter-Dennerlein, Ricarda, Oeljeklaus, Silke, Lorenzi, Isotta, Ronsör, Christin, Bareth, Bettina, Schendzielorz, Alexander Benjamin, Wang, Cong, Warscheid, Bettina, Rehling, Peter, Dennerlein, Sven
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 06.10.2016
Schlagworte:	Active Transport, Cell Nucleus Cell Line, Tumor Cyclooxygenase 1 - biosynthesis Cyclooxygenase 1 - genetics Cyclooxygenase 1 - metabolism DNA, Mitochondrial - genetics Electron Transport Complex IV - biosynthesis Electron Transport Complex IV - genetics Electron Transport Complex IV - metabolism HEK293 Cells Humans Membrane Proteins - biosynthesis Membrane Proteins - genetics Membrane Proteins - metabolism Mitochondria - enzymology Mitochondrial Proteins - biosynthesis Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Oxidative Phosphorylation Ribosomes - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics RNA, Mitochondrial mitochondrial translation assembly OXPHOS C12ORF62 COX1 cytochrome c oxidase translation regulation mitochondrial ribosome MITRAC translational plasticity
ISSN:	1097-4172, 1097-4172
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