Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution

In recently developed approaches for high-resolution imaging within intact tissue, molecular characterization over large volumes has been largely restricted to labeling of proteins. But volumetric nucleic acid labeling may represent a far greater scientific and clinical opportunity, enabling detecti...

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Bibliographic Details
Published in:Cell Vol. 164; no. 4; p. 792
Main Authors: Sylwestrak, Emily Lauren, Rajasethupathy, Priyamvada, Wright, Matthew Arnot, Jaffe, Anna, Deisseroth, Karl
Format: Journal Article
Language:English
Published: United States 11.02.2016
Subjects:
Adolescent
Animals
Brain Chemistry
Cyanates - chemistry
Ethyldimethylaminopropyl Carbodiimide - chemistry
Female
Humans
In Situ Hybridization - methods
Male
Maleimides - chemistry
Mice
Middle Aged
Nucleic Acid Amplification Techniques - methods
Oligonucleotides - chemistry
RNA - analysis
Succinimides - chemistry
Transcriptome
ISSN:1097-4172, 1097-4172
Online Access:Get more information
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