Oropouche Virus Disease Among U.S. Travelers — United States, 2024

Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in South America and the Caribbean. The virus is spread to humans by infected biting midges and some mosquito species. Although infection typicall...

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Vydáno v:MMWR. Morbidity and mortality weekly report Ročník 73; číslo 35; s. 769 - 773
Hlavní autoři: Morrison, Andrea, White, Jennifer L., Hughes, Holly R., Guagliardo, Sarah Anne J., Velez, Jason O., Fitzpatrick, Kelly A., Davis, Emily H., Stanek, Danielle, Kopp, Edgar, Dumoulin, Peter, Locksmith, Timothy, Heberlein, Lea, Zimler, Rebecca, Lassen, Joshua, Bestard, Carolina, Rico, Edhelene, Mejia-Echeverri, Alvaro, Edwards-Taylor, Kay-Anna, Holt, Douglas, Halphen, Dionisia, Peters, Kaitlynn, Adams, Cheryl, Nichols, Amanda M., Ciota, Alexander T., Dupuis, Alan P., Backenson, P. Bryon, Lehman, Jennifer A., Lyons, Shelby, Padda, Hannah, Connelly, Roxanne C., Tong, Van T., Martin, Stacey W., Lambert, Amy J., Brault, Aaron C., Blackmore, Carina, Staples, J. Erin, Gould, Carolyn V.
Médium: Journal Article Newsletter
Jazyk:angličtina
Vydáno: United States U.S. Government Printing Office 05.09.2024
U.S. Center for Disease Control
Centers for Disease Control and Prevention
Témata:
ISSN:0149-2195, 1545-861X, 1545-861X
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Abstract Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in South America and the Caribbean. The virus is spread to humans by infected biting midges and some mosquito species. Although infection typically causes a self-limited febrile illness, reports of two deaths in patients with Oropouche virus infection and vertical transmission associated with adverse pregnancy outcomes have raised concerns about the threat of this virus to human health. In addition to approximately 8,000 locally acquired cases in the Americas, travel-associated Oropouche virus disease cases have recently been identified in European travelers returning from Cuba and Brazil. As of August 16, 2024, a total of 21 Oropouche virus disease cases were identified among U.S. travelers returning from Cuba. Most patients initially experienced fever, myalgia, and headache, often with other symptoms including arthralgia, diarrhea, nausea or vomiting, and rash. At least three patients had recurrent symptoms after the initial illness, a common characteristic of Oropouche virus disease. Clinicians and public health jurisdictions should be aware of the occurrence of Oropouche virus disease in U.S. travelers and request testing for suspected cases. Travelers should prevent insect bites when traveling, and pregnant persons should consider deferring travel to areas experiencing outbreaks of Oropouche virus disease.
AbstractList Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in South America and the Caribbean. The virus is spread to humans by infected biting midges and some mosquito species. Although infection typically causes a self-limited febrile illness, reports of two deaths in patients with Oropouche virus infection and vertical transmission associated with adverse pregnancy outcomes have raised concerns about the threat of this virus to human health. In addition to approximately 8,000 locally acquired cases in the Americas, travel-associated Oropouche virus disease cases have recently been identified in European travelers returning from Cuba and Brazil. As of August 16, 2024, a total of 21 Oropouche virus disease cases were identified among U.S. travelers returning from Cuba. Most patients initially experienced fever, myalgia, and headache, often with other symptoms including arthralgia, diarrhea, nausea or vomiting, and rash. At least three patients had recurrent symptoms after the initial illness, a common characteristic of Oropouche virus disease. Clinicians and public health jurisdictions should be aware of the occurrence of Oropouche virus disease in U.S. travelers and request testing for suspected cases. Travelers should prevent insect bites when traveling, and pregnant persons should consider deferring travel to areas experiencing outbreaks of Oropouche virus disease.
What is already known about this topic? Oropouche virus is an emerging arthropod-borne virus in the Americas. Recent reports of outbreaks in areas without previous endemic transmission, fatal cases, and vertical transmission associated with adverse pregnancy outcomes have raised concerns about human health risks. What is added by this report? As of August 16, 2024, a total of 21 Oropouche virus disease cases among U.S. travelers returning from Cuba have been reported. Most patients had self-limited illness. At least three patients experienced recurrent symptoms after resolution of the initial illness. What are the implications for public health practice? Clinicians and public health jurisdictions should be aware of the occurrence of Oropouche virus disease in U.S. travelers and request testing for suspected cases. Travelers should prevent insect bites when traveling, and pregnant persons should consider deferring travel to areas experiencing outbreaks of Oropouche virus disease.
Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in South America and the Caribbean. The virus is spread to humans by infected biting midges and some mosquito species. Although infection typically causes a self-limited febrile illness, reports of two deaths in patients with Oropouche virus infection and vertical transmission associated with adverse pregnancy outcomes have raised concerns about the threat of this virus to human health. In addition to approximately 8,000 locally acquired cases in the Americas, travel-associated Oropouche virus disease cases have recently been identified in European travelers returning from Cuba and Brazil. As of August 16, 2024, a total of 21 Oropouche virus disease cases were identified among U.S. travelers returning from Cuba. Most patients initially experienced fever, myalgia, and headache, often with other symptoms including arthralgia, diarrhea, nausea or vomiting, and rash. At least three patients had recurrent symptoms after the initial illness, a common characteristic of Oropouche virus disease. Clinicians and public health jurisdictions should be aware of the occurrence of Oropouche virus disease in U.S. travelers and request testing for suspected cases. Travelers should prevent insect bites when traveling, and pregnant persons should consider deferring travel to areas experiencing outbreaks of Oropouche virus disease.Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in South America and the Caribbean. The virus is spread to humans by infected biting midges and some mosquito species. Although infection typically causes a self-limited febrile illness, reports of two deaths in patients with Oropouche virus infection and vertical transmission associated with adverse pregnancy outcomes have raised concerns about the threat of this virus to human health. In addition to approximately 8,000 locally acquired cases in the Americas, travel-associated Oropouche virus disease cases have recently been identified in European travelers returning from Cuba and Brazil. As of August 16, 2024, a total of 21 Oropouche virus disease cases were identified among U.S. travelers returning from Cuba. Most patients initially experienced fever, myalgia, and headache, often with other symptoms including arthralgia, diarrhea, nausea or vomiting, and rash. At least three patients had recurrent symptoms after the initial illness, a common characteristic of Oropouche virus disease. Clinicians and public health jurisdictions should be aware of the occurrence of Oropouche virus disease in U.S. travelers and request testing for suspected cases. Travelers should prevent insect bites when traveling, and pregnant persons should consider deferring travel to areas experiencing outbreaks of Oropouche virus disease.
Audience Professional
Author Bestard, Carolina
Holt, Douglas
Halphen, Dionisia
Backenson, P. Bryon
Gould, Carolyn V.
Nichols, Amanda M.
Staples, J. Erin
Dumoulin, Peter
Locksmith, Timothy
Edwards-Taylor, Kay-Anna
Blackmore, Carina
Rico, Edhelene
Tong, Van T.
Fitzpatrick, Kelly A.
Adams, Cheryl
Heberlein, Lea
Dupuis, Alan P.
Velez, Jason O.
Lyons, Shelby
Hughes, Holly R.
Stanek, Danielle
Lehman, Jennifer A.
Brault, Aaron C.
Davis, Emily H.
Lassen, Joshua
Ciota, Alexander T.
Zimler, Rebecca
Morrison, Andrea
Lambert, Amy J.
White, Jennifer L.
Connelly, Roxanne C.
Kopp, Edgar
Guagliardo, Sarah Anne J.
Mejia-Echeverri, Alvaro
Peters, Kaitlynn
Padda, Hannah
Martin, Stacey W.
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/39236058$$D View this record in MEDLINE/PubMed
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10.2807/1560-7917.ES.2024.29.26.2400362
10.3201/eid1306.061114
10.1590/0074-02760160062
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OpenAccessLink https://pubmed.ncbi.nlm.nih.gov/PMC11376504
PMID 39236058
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PublicationCentury 2000
PublicationDate 2024-09-05
2024-Sep-05
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  year: 2024
  text: 2024-09-05
  day: 05
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PublicationPlace United States
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PublicationTitle MMWR. Morbidity and mortality weekly report
PublicationTitleAlternate MMWR Morb Mortal Wkly Rep
PublicationYear 2024
Publisher U.S. Government Printing Office
U.S. Center for Disease Control
Centers for Disease Control and Prevention
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References key-10.15585/mmwr.mm7335e1-202409042325-R8
Azevedo (key-10.15585/mmwr.mm7335e1-202409042325-R2) 2007; 13
key-10.15585/mmwr.mm7335e1-202409042325-R3
Durango-Chavez (key-10.15585/mmwr.mm7335e1-202409042325-R4) 2022; 17
key-10.15585/mmwr.mm7335e1-202409042325-R1
Naveca (key-10.15585/mmwr.mm7335e1-202409042325-R6) 2017; 112
Castilletti (key-10.15585/mmwr.mm7335e1-202409042325-R7) 2024; 29
key-10.15585/mmwr.mm7335e1-202409042325-R5
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– ident: key-10.15585/mmwr.mm7335e1-202409042325-R5
– volume: 17
  start-page: e0270294
  year: 2022
  ident: key-10.15585/mmwr.mm7335e1-202409042325-R4
  article-title: Oropouche virus infection in patients with acute febrile syndrome: is a predictive model based solely on signs and symptoms useful?
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0270294
– ident: key-10.15585/mmwr.mm7335e1-202409042325-R1
– ident: key-10.15585/mmwr.mm7335e1-202409042325-R8
– volume: 29
  start-page: 2400362
  year: 2024
  ident: key-10.15585/mmwr.mm7335e1-202409042325-R7
  article-title: Oropouche fever cases diagnosed in Italy in two epidemiologically non-related travellers from Cuba, late May to early June 2024.
  publication-title: Euro Surveill
  doi: 10.2807/1560-7917.ES.2024.29.26.2400362
– volume: 13
  start-page: 912
  year: 2007
  ident: key-10.15585/mmwr.mm7335e1-202409042325-R2
  article-title: Reemergence of Oropouche fever, northern Brazil.
  publication-title: Emerg Infect Dis
  doi: 10.3201/eid1306.061114
– volume: 112
  start-page: 510
  year: 2017
  ident: key-10.15585/mmwr.mm7335e1-202409042325-R6
  article-title: Multiplexed reverse transcription real-time polymerase chain reaction for simultaneous detection of Mayaro, Oropouche, and Oropouche-like viruses.
  publication-title: Mem Inst Oswaldo Cruz
  doi: 10.1590/0074-02760160062
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Snippet Beginning in late 2023, Oropouche virus was identified as the cause of large outbreaks in Amazon regions with known endemic transmission and in new areas in...
What is already known about this topic? Oropouche virus is an emerging arthropod-borne virus in the Americas. Recent reports of outbreaks in areas without...
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StartPage 769
SubjectTerms Adult
Aged
Bites and stings
Bunyaviridae Infections - epidemiology
Congenital diseases
Cuba
Cuba - epidemiology
Dengue fever
Departments
Diarrhea
Disease
Disease Outbreaks
Disease prevention
Disease transmission
Female
Florida
Full Report
Headaches
Health aspects
Health risks
Humans
Illnesses
Infection
Infections
Insect bites
Insects
Male
Medical laboratories
Middle Aged
Mosquitoes
Orthobunyavirus - isolation & purification
Outbreaks
Pain
Patients
Pest outbreaks
Pregnancy
Pregnant women
Public health
Recurrent
South America
Travel
Travel-Related Illness
Travelers
United States - epidemiology
Vertical transmission (disease)
Virus diseases
Viruses
Vomiting
Young Adult
Zika virus
Title Oropouche Virus Disease Among U.S. Travelers — United States, 2024
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