Mechanisms of pathological scarring: Role of myofibroblasts and current developments

ABSTRACT Myofibroblasts play a key role in the wound‐healing process, promoting wound closure and matrix deposition. These cells normally disappear from granulation tissue by apoptosis after wound closure, but under some circumstances, they persist and may contribute to pathological scar formation....

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Vydáno v:	Wound repair and regeneration Ročník 19; číslo s1; s. s10 - s15
Hlavní autoři:	Sarrazy, Vincent, Billet, Fabrice, Micallef, Ludovic, Coulomb, Bernard, Desmoulière, Alexis
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Malden, USA Blackwell Publishing Inc 01.09.2011
Témata:	Cicatrix - physiopathology Cicatrix, Hypertrophic - physiopathology Granulation Tissue - physiology Humans Keloid - physiopathology Liver - physiopathology Myofibroblasts - cytology Myofibroblasts - physiology Neoplasms - physiopathology Stress, Mechanical Transforming Growth Factor beta1 - physiology Wound Healing - physiology
ISSN:	1067-1927, 1524-475X, 1524-475X
On-line přístup:	Získat plný text
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