ELTD1 is present in extracellular vesicles derived from endothelial cells as a cleaved extracellular domain which induces in vivo angiogenesis

ELTD1/ADGRL4 is an adhesion GPCR with an important role in angiogenesis. We recently identified a role for ELTD1 in wound repair and inflammation. Activation of ELTD1 in endothelial cells results in a type II EMT to myofibroblast‐like cells that have enhanced angiogenic ability. Furthermore, express...

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Veröffentlicht in:	Journal of extracellular biology Jg. 1; H. 8; S. e52 - n/a
Hauptverfasser:	Sheldon, Helen, Zhang, Wei, Bridges, Esther, Ang, Koon Hwee, Lin, Salwa, Masiero, Massimo, Li, Demin, Handford, Penny A., Whiteman, Pat, Fischer, Roman, Buffa, Francesca, Vatish, Manu, Banham, Alison H., Harris, Adrian L.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States John Wiley & Sons, Inc 01.08.2022 John Wiley and Sons Inc Wiley
Schlagworte:	Angiogenesis Antibodies Biomarkers Cell activation Cell size Cells Cloning ELTD1 Endothelial cells Endothelium Epidermal growth factor Extracellular vesicles Flow cytometry G protein-coupled receptors Immune response Inflammation Manufacturers Mass spectroscopy Microenvironments migrasomes Pre-eclampsia Proteins Proteomics Wound healing United Kingdom > UK Fiji migrasomes ELTD1 extracellular vesicles angiogenesis
ISSN:	2768-2811, 2768-2811
Online-Zugang:	Volltext
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