Poly(l-Lactic Acid)/Gelatin Fibrous Scaffold Loaded with Simvastatin/Beta-Cyclodextrin-Modified Hydroxyapatite Inclusion Complex for Bone Tissue Regeneration

Recently, the application of nanostructured materials in the field of tissue engineering has garnered attention to mediate treatment and regeneration of bone defects. In this study, poly(l‐lactic acid) (PLLA)/gelatin (PG) fibrous scaffolds are fabricated and β‐cyclodextrin (βCD) grafted nano‐hydroxy...

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Veröffentlicht in:	Macromolecular bioscience Jg. 16; H. 7; S. 1027 - 1038
Hauptverfasser:	Lee, Jung Bok, Kim, Ji Eun, Balikov, Daniel A., Bae, Min Soo, Heo, Dong Nyoung, Lee, Donghyun, Rim, Hyun Joon, Lee, Deok-Won, Sung, Hak-Joon, Kwon, Il Keun
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany Blackwell Publishing Ltd 01.07.2016 Wiley Subscription Services, Inc
Schlagworte:	adamantine adipose derived stem cell Animals beta-cyclodextrin beta-Cyclodextrins - chemistry Bone Development - drug effects bone tissue engineering Cell Differentiation - drug effects Durapatite - administration & dosage Durapatite - chemistry Gelatin - administration & dosage Gelatin - chemistry Gene expression Humans Hydroxyapatite Mineralization Nanostructured materials Osteogenesis - drug effects Polyesters - administration & dosage Polyesters - chemistry Rabbits simvastatin Simvastatin - administration & dosage Simvastatin - chemistry Stem cells Tissue Engineering Tissue Scaffolds - chemistry Wound Healing - drug effects adipose derived stem cell simvastatin beta-cyclodextrin adamantine bone tissue engineering
ISSN:	1616-5187, 1616-5195, 1616-5195
Online-Zugang:	Volltext
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