The cGAS-STING pathway for DNA sensing

The nucleotidyl transferase cGAS, its second-messenger product cGAMP, and the cGAMP sensor STING form the basic mechanism of DNA sensing in the cytoplasm of mammalian cells. Several new reports now uncover key structural features associated with DNA recognition by cGAS and the catalytic mechanisms o...

Full description

Saved in:

Bibliographic Details
Published in:	Molecular cell Vol. 51; no. 2; p. 135
Main Authors:	Xiao, T Sam, Fitzgerald, Katherine A
Format:	Journal Article
Language:	English
Published:	United States 25.07.2013
Subjects:	Biosensing Techniques DNA - metabolism Humans Membrane Proteins - metabolism Nucleotidyltransferases - metabolism Second Messenger Systems
ISSN:	1097-4164, 1097-4164
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!